How do I take RUXIENCE?


RUXIENCE is given by infusion through a needle placed in a vein (intravenous infusion)


Your doctor may prescribe medicines before each infusion of RUXIENCE to reduce side effects of infusions such as fever and chills


Your doctor will do regular blood tests to check for side effects to RUXIENCE


RUXIENCE may be given the same way as Rituxan® (rituximab)


Before each RUXIENCE treatment, your doctor or nurse will ask you questions about your general health


Be sure to tell your doctor or nurse about any new symptoms

Serious side effects of RUXIENCE

RUXIENCE can cause serious side effects that can lead to death. Some of them may be life-threatening. Your doctor will stop treatment if any serious side effects occur.

Be sure to contact your healthcare team if there are any signs of these side effects.

Serious side effects include:

Infusion-related reactions

These include hives or rash; itching; swelling of your lips, tongue, throat, or face; sudden cough; shortness of breath, difficulty breathing, or wheezing; weakness; dizziness or feeling faint; palpitations; or chest pain. These can happen during your infusion or within 24 hours after your infusion.

Severe skin and mouth reactions

These include painful sores or ulcers on your skin, lips, or in your mouth; blisters; peeling skin; rash; or pustules.

Hepatitis B virus (HBV) reactivation

May cause serious liver problems, including liver failure, and death. If you have had hepatitis B or are a carrier of HBV, receiving RUXIENCE could cause the virus to become an active infection again.

Progressive multifocal leukoencephalopathy (PML)

PML is a rare, serious brain infection caused by a virus that can happen in people who receive RUXIENCE. People with weakened immune systems can get PML.

Discuss your RUXIENCE treatment schedule with your healthcare provider.